Búsqueda | Biblioteca Virtual en Salud Odontología. Uruguay

1.

Combining single-cell tracking and omics improves blood stem cell fate regulator identification.

Wehling, A; Loeffler, D; Zhang, Y; Kull, T; Donato, C; Szczerba, B; Camargo Ortega, G; Lee, M; Moor, A; Göttgens, B; Aceto, N; Schroeder, T.

Blood ; 140(13): 1482-1495, 2022 09 29.

Artículo en Inglés | MEDLINE | ID: mdl-35820055

2.

A genome-wide relay of signalling-responsive enhancers drives hematopoietic specification.

Edginton-White, B; Maytum, A; Kellaway, S G; Goode, D K; Keane, P; Pagnuco, I; Assi, S A; Ames, L; Clarke, M; Cockerill, P N; Göttgens, B; Cazier, J B; Bonifer, C.

Nat Commun ; 14(1): 267, 2023 01 17.

Artículo en Inglés | MEDLINE | ID: mdl-36650172

3.

Integration of spatial and single-cell transcriptomic data elucidates mouse organogenesis.

Lohoff, T; Ghazanfar, S; Missarova, A; Koulena, N; Pierson, N; Griffiths, J A; Bardot, E S; Eng, C-H L; Tyser, R C V; Argelaguet, R; Guibentif, C; Srinivas, S; Briscoe, J; Simons, B D; Hadjantonakis, A-K; Göttgens, B; Reik, W; Nichols, J; Cai, L; Marioni, J C.

Nat Biotechnol ; 40(1): 74-85, 2022 01.

Artículo en Inglés | MEDLINE | ID: mdl-34489600

4.

The SCL +40 enhancer targets the midbrain together with primitive and definitive hematopoiesis and is regulated by SCL and GATA proteins.

Ogilvy, S; Ferreira, R; Piltz, S G; Bowen, J M; Göttgens, B; Green, A R.

Mol Cell Biol ; 27(20): 7206-19, 2007 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-17709394

5.

Transcriptional regulation of the SCL locus: identification of an enhancer that targets the primitive erythroid lineage in vivo.

Delabesse, E; Ogilvy, S; Chapman, M A; Piltz, S G; Gottgens, B; Green, A R.

Mol Cell Biol ; 25(12): 5215-25, 2005 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-15923636

6.

Analysis of vertebrate SCL loci identifies conserved enhancers.

Göttgens, B; Barton, L M; Gilbert, J G; Bench, A J; Sanchez, M J; Bahn, S; Mistry, S; Grafham, D; McMurray, A; Vaudin, M; Amaya, E; Bentley, D R; Green, A R; Sinclair, A M.

Nat Biotechnol ; 18(2): 181-6, 2000 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-10657125

7.

Genome-scale definition of the transcriptional programme associated with compromised PU.1 activity in acute myeloid leukaemia.

Sive, J I; Basilico, S; Hannah, R; Kinston, S J; Calero-Nieto, F J; Göttgens, B.

Leukemia ; 30(1): 14-23, 2016 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-26126967

8.

The epigenetic regulators CBP and p300 facilitate leukemogenesis and represent therapeutic targets in acute myeloid leukemia.

Giotopoulos, G; Chan, W-I; Horton, S J; Ruau, D; Gallipoli, P; Fowler, A; Crawley, C; Papaemmanuil, E; Campbell, P J; Göttgens, B; Van Deursen, J M; Cole, P A; Huntly, B J P.

Oncogene ; 35(3): 279-89, 2016 Jan 21.

Artículo en Inglés | MEDLINE | ID: mdl-25893291

9.

The gene encoding hematopoietic cell phosphatase (SHP-1) is structurally and transcriptionally intact in polycythemia vera.

Asimakopoulos, F A; Hinshelwood, S; Gilbert, J G; Delibrias, C C; Göttgens, B; Fearon, D T; Green, A R.

Oncogene ; 14(10): 1215-22, 1997 Mar 13.

Artículo en Inglés | MEDLINE | ID: mdl-9121771

10.

Discordant regulation of SCL/TAL-1 mRNA and protein during erythroid differentiation.

Murrell, A M; Bockamp, E O; Göttgens, B; Chan, Y S; Cross, M A; Heyworth, C M; Green, A R.

Oncogene ; 11(1): 131-9, 1995 Jul 06.

Artículo en Inglés | MEDLINE | ID: mdl-7624120

11.

Transcription of the SCL gene in erythroid and CD34 positive primitive myeloid cells is controlled by a complex network of lineage-restricted chromatin-dependent and chromatin-independent regulatory elements.

Göttgens, B; McLaughlin, F; Bockamp, E O; Fordham, J L; Begley, C G; Kosmopoulos, K; Elefanty, A G; Green, A R.

Oncogene ; 15(20): 2419-28, 1997 Nov 13.

Artículo en Inglés | MEDLINE | ID: mdl-9395238

12.

Chromatin structure and transcriptional regulation of the stem cell leukaemia (SCL) gene in mast cells.

Fordham, J L; Göttgens, B; McLaughlin, F; Green, A R.

Leukemia ; 13(5): 750-9, 1999 May.

Artículo en Inglés | MEDLINE | ID: mdl-10374880

13.

Tdr2, a new zebrafish transposon of the Tc1 family.

Göttgens, B; Barton, L M; Grafham, D; Vaudin, M; Green, A R.

Gene ; 239(2): 373-9, 1999 Nov 01.

Artículo en Inglés | MEDLINE | ID: mdl-10548740

14.

BET protein inhibition shows efficacy against JAK2V617F-driven neoplasms.

Wyspianska, B S; Bannister, A J; Barbieri, I; Nangalia, J; Godfrey, A; Calero-Nieto, F J; Robson, S; Rioja, I; Li, J; Wiese, M; Cannizzaro, E; Dawson, M A; Huntly, B; Prinjha, R K; Green, A R; Gottgens, B; Kouzarides, T.

Leukemia ; 28(1): 88-97, 2014 Jan.

Artículo en Inglés | MEDLINE | ID: mdl-23929215

15.

HOX-mediated LMO2 expression in embryonic mesoderm is recapitulated in acute leukaemias.

Calero-Nieto, F J; Joshi, A; Bonadies, N; Kinston, S; Chan, W-I; Gudgin, E; Pridans, C; Landry, J-R; Kikuchi, J; Huntly, B J; Gottgens, B.

Oncogene ; 32(48): 5471-80, 2013 Nov 28.

Artículo en Inglés | MEDLINE | ID: mdl-23708655

16.

Bivalent promoter marks and a latent enhancer may prime the leukaemia oncogene LMO1 for ectopic expression in T-cell leukaemia.

Oram, S H; Thoms, J; Sive, J I; Calero-Nieto, F J; Kinston, S J; Schütte, J; Knezevic, K; Lock, R B; Pimanda, J E; Göttgens, B.

Leukemia ; 27(6): 1348-57, 2013 Jun.

Artículo en Inglés | MEDLINE | ID: mdl-23302769

17.

A previously unrecognized promoter of LMO2 forms part of a transcriptional regulatory circuit mediating LMO2 expression in a subset of T-acute lymphoblastic leukaemia patients.

Oram, S H; Thoms, J A I; Pridans, C; Janes, M E; Kinston, S J; Anand, S; Landry, J-R; Lock, R B; Jayaraman, P-S; Huntly, B J; Pimanda, J E; Göttgens, B.

Oncogene ; 29(43): 5796-808, 2010 Oct 28.

Artículo en Inglés | MEDLINE | ID: mdl-20676125

18.

The stem cell leukaemia (SCL) gene: a critical regulator of haemopoietic and vascular development.

Barton, L M; Göttgens, B; Green, A R.

Int J Biochem Cell Biol ; 31(10): 1193-207, 1999 Oct.

Artículo en Inglés | MEDLINE | ID: mdl-10582347

19.

Delineating MEIS1 cis-regulatory elements active in hematopoietic cells.

Xiang, P; Wei, W; Lo, C; Rosten, P; Hou, J; Hoodless, P A; Bilenky, M; Bonifer, C; Cockerill, P N; Kirkpatrick, A; Gottgens, B; Hirst, M; Humphries, K R.

Leukemia ; 28(2): 433-6, 2014 Feb.

Artículo en Inglés | MEDLINE | ID: mdl-24097337

20.

Retinoic acid and the differentiation of lymphohaemopoietic stem cells.

Göttgens, B; Green, A R.

Bioessays ; 17(3): 187-9, 1995 Mar.

Artículo en Inglés | MEDLINE | ID: mdl-7748171

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